Drug-specific improvement in ADHD symptoms was highly significant overall (42% decrease on the ADHD Rating Scale, P or =30%) was significantly higher with Adderall treatment than with a placebo (70% vs 7% P =.001).Īdderall was effective and well tolerated in the short-term treatment of adults with ADHD. Efficacy of a mixed amphetamine salts compound in adults with attention-deficit/hyperactivity disorder. Adults 18 years of age were given placebo or MAS XR 20, 40, or.
Treatment with Adderall at an average oral dose of 54 mg (administered in 2 daily doses) was effective and well tolerated. Method: This prospective, multisite, randomized, double-blind, placebo-controlled, parallel-group, dose-escalation study was conducted to assess the efficacy, safety, and duration of action of mixed amphetamine salts extended-release (MAS XR) in adults with ADHD, combined type.
It should be taken first thing in the morning. Comorbid psychiatric disorders were assessed to test for potential effects on treatment outcome. Mixed amphetamine salts are available as extended-release capsules (Adderall XR) that are taken by mouth. Outcome measures included the ADHD Rating Scale and the Clinical Global Impression Score. Medication was titrated up to 30 mg twice a day.
MIXED AMPHETAMINE SALTS FULL
This was a 7-week, randomized, double-blind, placebo-controlled, crossover study of Adderall in 27 well-characterized adults satisfying full DSM-IV criteria for ADHD of childhood onset and persistent symptoms into adulthood. Company Contact Information: 73 Presentation Amphetamine Mixed Salts Tablets C-II 5 mg, 100 (NDC 13107-0068-01) Amphetamine Mixed Salts Tablets C-II 10 mg, 100 (NDC 13107-0070-01).
MIXED AMPHETAMINE SALTS TRIAL
More work is needed to evaluate the long-term effects of Adderall, or other amphetamine compounds, in the treatment of adults with ADHD.We report on a controlled trial of a mixed amphetamine salts compound (Adderall, dextroamphetamine sulfate, dextro-, levoamphetamine sulfate, dextroamphetamine aspartate, levoamphetamine aspartate, and dextroamphetamine saccharate) in the treatment of adult attention-deficit/hyperactivity disorder (ADHD). Drug-specific improvement in ADHD symptoms was highly significant overall (42% decrease on the ADHD Rating Scale, P or =30%) was significantly higher with Adderall treatment than with a placebo (70% vs 7% P =.001).Īdderall was effective and well tolerated in the short-term treatment of adults with ADHD. Treatment with Adderall at an average oral dose of 54 mg (administered in 2 daily doses) was effective and well tolerated. Comorbid psychiatric disorders were assessed to test for potential effects on treatment outcome. This was a 7-week, randomized, double-blind, placebo-controlled, crossover study of Adderall in 27 well-characterized adults satisfying full DSM-IV criteria for ADHD of childhood onset and persistent symptoms into adulthood. We report on a controlled trial of a mixed amphetamine salts compound (Adderall, dextroamphetamine sulfate, dextro-, levoamphetamine sulfate, dextroamphetamine aspartate, levoamphetamine aspartate, and dextroamphetamine saccharate) in the treatment of adult attention-deficit/hyperactivity disorder (ADHD).